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There are several matches for 'glutamate--cysteine ligase'.
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10083 matches
showing page 1 of 505
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organism
protein
1)
Drosophila melanogaster
Gclc -
Glutamate
-
cysteine
ligase
catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-
cysteine
and L-
glutamate
to form gamma-glutamylcysteine; Belongs to the
glutamate
--
cysteine
ligase
type 3 family.
[a.k.a. FBgn0040319, Gclc-PC, Gclc-PB,
Glutamate--cysteine ligase
]
2)
Caenorhabditis elegans
gcs-1 -
Glutamate
--
cysteine
ligase
; Plays a role in resistance to arsenite. May play a role in the oxidative stress response induced by reactive oxygen species produced during infection by pathogenic bacteria. Together with trxr-1, required for the reduction of disulfide groups in the cuticle during molting.
[a.k.a. F37B12.2, Gcs-1, GCS,
Glutamate--cysteine ligase
]
3)
Escherichia coli K12
gshA -
Glutamate
-
cysteine
ligase
; Protein involved in glutathione biosynthetic process; Belongs to the
glutamate
--
cysteine
ligase
type 1 family. Type 1 subfamily.
[a.k.a. b2688, AAC75735.1, GCS,
Glutamate--cysteine ligase
]
4)
Saccharomyces cerevisiae
GSH1 -
Glutamate
--
cysteine
ligase
; Gamma glutamylcysteine synthetase; catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury; protein abundance increases in response to DNA replication stress; Belongs to the
glutamate
--
cysteine
ligase
type 3 family.
[a.k.a. YJL101C, sce:YJL101C, J0832,
Glutamate--cysteine ligase
,
glutamate--cysteine ligase
, ...]
5)
Homo sapiens
GCLM -
Glutamate
-
cysteine
ligase
modifier subunit; Belongs to the aldo/keto reductase family.
Glutamate
--
cysteine
ligase
light chain subfamily.
[a.k.a. P48507, ENST00000370238.7, XM_011541261]
6)
Homo sapiens
GCLC -
Glutamate
-
cysteine
ligase
catalytic subunit.
[a.k.a. UPI0000415252, UPI0001D3BBDB, LRG_1166]
7)
Mus musculus
Gclc -
Glutamate
--
cysteine
ligase
catalytic subunit; Belongs to the
glutamate
--
cysteine
ligase
type 3 family.
[a.k.a. ENSMUSP00000034905, R-MMU-156580, 14629]
8)
Mus musculus
Gclm -
Glutamate
--
cysteine
ligase
regulatory subunit; Belongs to the aldo/keto reductase family.
Glutamate
--
cysteine
ligase
light chain subfamily.
[a.k.a. ENSMUSG00000028124, ENSMUST00000178826.7, R-MMU-156580]
9)
Drosophila melanogaster
Gclm -
Glutamate
-
cysteine
ligase
modifier subunit (Gclm) encodes a protein that regulates the
ligase
activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol.
[a.k.a. FBgn0046114, Gclm-PB, Gclm-PA]
10)
Escherichia coli K12
ybdK - Weak gamma-glutamyl:
cysteine
ligase
; ATP-dependent carboxylate-amine
ligase
which exhibits weak
glutamate
--
cysteine
ligase
activity. However, because of the low catalytic rate, the question remains whether L-
cysteine
is the actual biological substrate; Belongs to the
glutamate
--
cysteine
ligase
type 2 family. YbdK subfamily.
[a.k.a. b0581, AAC73682.1, JW0570]
11)
Escherichia coli K12
ygiC - ATP-Grasp family ATPase; May be a
ligase
forming an amide bond. Shows ATPase activity. Despite its similarity to the C-terminal synthetase domain of Gss, is not a glutathionylspermidine (Gsp) synthetase. Cannot synthesize Gsp, glutathione (GSH), or GSH intermediates, from GSH and spermidine,
cysteine
and
glutamate
, gamma-glutamylcysteine and spermidine, and gamma-glutamylcysteine and glycine. Does not bind to Gsp. Belongs to the glutathionylspermidine synthase preATP-grasp family.
[a.k.a. b3038, AAC76074.1, P0ADT5]
12)
Escherichia coli K12
yjfC - ATP-Grasp family ATPase; May be a
ligase
forming an amide bond. Shows ATPase activity. Despite its similarity to the C-terminal synthetase domain of Gss, is not a glutathionylspermidine (Gsp) synthetase. Cannot synthesize Gsp, glutathione (GSH), or GSH intermediates, from GSH and spermidine,
cysteine
and
glutamate
, gamma-glutamylcysteine and spermidine, and gamma-glutamylcysteine and glycine. Does not bind to Gsp. Belongs to the glutathionylspermidine synthase preATP-grasp family.
[a.k.a. b4186, AAC77143.1, Putative acid--amine ligase YjfC]
13)
Acaryochloris marina
gshA -
Glutamate
--
cysteine
ligase
, putative.
[a.k.a. AM1_1510, ABW26535.1, NC_009925.1,
Glutamate--cysteine ligase
]
14)
Accumulibacter phosphatis
ACV34019.1 - TIGRFAM: glutamate/cysteine
ligase
; PFAM:
glutamate
--
cysteine
ligase
GshA; KEGG: dar:Daro_0011
glutamate
--
cysteine
ligase
GshA.
[a.k.a. CAP2UW1_0673, NC_013194.1, EC 6.3.2.2,
Glutamate--cysteine ligase
]
15)
Accumulibacter sp. 6626
OJW48939.1 -
Glutamate
--
cysteine
ligase
; ATP-dependent carboxylate-amine
ligase
which exhibits weak
glutamate
--
cysteine
ligase
activity; Belongs to the
glutamate
--
cysteine
ligase
type 2 family. YbdK subfamily.
[a.k.a. BGO63_06205, GCS 2, A0A1Q3VQW1_9PROT,
glutamate--cysteine ligase
,
Glutamate--cysteine ligase
, ...]
16)
Accumulibacter sp. 6626
OJW49520.1 -
Glutamate
--
cysteine
ligase
; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. BGO63_09680, A0A1Q3VS15,
Glutamate--cysteine ligase
,
glutamate--cysteine ligase
]
17)
Accumulibacter sp. BA92
gshA -
Glutamate
--
cysteine
ligase
; Belongs to the
glutamate
--
cysteine
ligase
type 1 family. Type 1 subfamily.
[a.k.a. EXI82182.1, AW10_00629, GCS,
Glutamate--cysteine ligase
]
18)
Accumulibacter sp. BA92
AW10_01321 - Carboxylate-amine ligase.
[a.k.a. EXI81121.1, EXI81121, 6.3.2.2,
Glutamate--cysteine ligase
]
19)
Accumulibacter sp. BA93
gshA -
Glutamate
--
cysteine
ligase
; Belongs to the
glutamate
--
cysteine
ligase
type 1 family. Type 1 subfamily.
[a.k.a. AW11_01533, EXI89442.1, GCS,
Glutamate--cysteine ligase
]
20)
Accumulibacter sp. BA93
AW11_03159 - Carboxylate-amine ligase.
[a.k.a. EXI86380.1, 6.3.2.2, A0A011QB83_9PROT,
Glutamate--cysteine ligase
]
10083 matches
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